S-Adenosylmethionine (SAMe) in major depressive disorder (MDD): a clinician-oriented systematic review

Abstract Background Major depressive disorder (MDD) is a recurrent illness with high rates of chronicity, treatment-resistance, and significant economic impact. S-Adenosylmethionine (SAMe), a molecule that is formed naturally in the human body, has shown antidepressant effects and may expand the ava...

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Bibliographic Details
Main Authors: Alessandro Cuomo, Bruno Beccarini Crescenzi, Simone Bolognesi, Arianna Goracci, Despoina Koukouna, Rodolfo Rossi, Andrea Fagiolini
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Annals of General Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12991-020-00298-z