An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

Abstract Lewy body dementias are the second most common cause of neurodegenerative dementia in the elderly after Alzheimer’s disease (AD). The two clinical subgroups of Lewy body dementias, namely, dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), are differentiated by the chro...

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Bibliographic Details
Main Authors: Arnab Datta, Yuek Ling Chai, Jing Min Tan, Jasinda H. Lee, Paul T. Francis, Christopher P. Chen, Siu Kwan Sze, Mitchell K. P. Lai
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Molecular Brain
Subjects:
Lewy body dementias
Dementia with Lewy bodies
Parkinson’s disease dementia
iTRAQ
Clinical proteomics
β-amyloid
Online Access:http://link.springer.com/article/10.1186/s13041-017-0316-9

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http://link.springer.com/article/10.1186/s13041-017-0316-9

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