Inhibition of extracellular matrix production and remodeling by doxycycline in smooth muscle cells

Alterations in the extracellular matrix (ECM) production and remodeling of smooth muscle cells (SMCs) have been implicated in processes related to the differentiation in atherosclerosis. Due to the anti-atherosclerotic properties of the tetracyclines, we aimed to investigate whether cholesterol supp...

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Bibliographic Details
Main Authors: Rogelio Palomino-Morales, Carolina Torres, Sonia Perales, Ana Linares, Maria Jose Alejandre
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300020