Anti-IL-2 treatment impairs the expansion of T(reg) cell population during acute malaria and enhances the Th1 cell response at the chronic disease.

Anti-IL-2 treatment impairs the expansion of T(reg) cell population during acute malaria and enhances the Th1 cell response at the chronic disease.

Plasmodium chabaudi infection induces a rapid and intense splenic CD4(+) T cell response that contributes to both disease pathogenesis and the control of acute parasitemia. The subsequent development of clinical immunity to disease occurs concomitantly with the persistence of low levels of chronic p...

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Bibliographic Details
Main Authors: Cláudia A Zago, Karina R Bortoluci, Luiz R Sardinha, Fernando D Pretel, Sheyla I Castillo-Méndez, Ana Paula Freitas do Rosário, Meire I Hiyane, Sandra M Muxel, Sérgio M Rodriguez-Málaga, Ises A Abrahamsohn, José M Álvarez, Maria Regina D'Império Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260167?pdf=render

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http://europepmc.org/articles/PMC3260167?pdf=render

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