Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data

Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data

Background and Objective: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality analysis (GCA). This approach analyses functional ma...

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Bibliographic Details
Main Authors: Yu Shi, Shaoye Cui, Yanyan Zeng, Shimin Huang, Guiyuan Cai, Jianming Yang, Wen Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
placebo analgesia
nocebo hyperalgesia
GCA
reward system
dopamine
anxiety
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.696577/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2021.696577/full

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