CRLF2 and IKZF1 abnormalities in Mexican children with acute lymphoblastic leukemia and recurrent gene fusions: exploring surrogate markers of signaling pathways

CRLF2 and IKZF1 abnormalities in Mexican children with acute lymphoblastic leukemia and recurrent gene fusions: exploring surrogate markers of signaling pathways

Abstract The gene fusions BCR‐ABL1, TCF3‐PBX1, and ETV6‐RUNX1 are recurrent in B‐cell acute lymphoblastic leukemia (B‐ALL) and are found with low frequency in coexistence with CRLF2 (cytokine receptor‐like factor 2) rearrangements and overexpression. There is limited information regarding the CRLF2...

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Bibliographic Details
Main Authors: Dafné Moreno Lorenzana, María del Rocío Juárez Velázquez, Adriana Reyes León, Daniel Martínez Anaya, Adrián Hernández Monterde, Consuelo Salas Labadía, María del Pilar Navarrete Meneses, Marta Zapata Tarrés, Luis Juárez Villegas, Berenice Jarquín Ramírez, Rocío Cárdenas Cardós, Martha Herrera Almanza, Rogelio Paredes Aguilera, Patricia Pérez Vera
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:The Journal of Pathology: Clinical Research
Subjects:
CRLF2
IKZF1
activated signaling pathways
acute lymphoblastic leukemia
primary rearrangements
Mexican children
Online Access:https://doi.org/10.1002/cjp2.211

Internet

https://doi.org/10.1002/cjp2.211

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