Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines

Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines

Abstract Background Although metastasis is ultimately responsible for about 90% of breast cancer mortality, the vast majority of breast-cancer-related deaths are due to progressive recurrences from non-metastatic disease. Current adjuvant therapies are unable to prevent progressive recurrences for a...

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Bibliographic Details
Main Authors: Sruthi Ravindranathan, Khue G. Nguyen, Samantha L. Kurtz, Haven N. Frazier, Sean G. Smith, Bhanu prasanth Koppolu, Narasimhan Rajaram, David A. Zaharoff
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Breast Cancer Research
Subjects:
Breast cancer vaccine
Autologous tumor cell vaccine
MDSCs
Breast cancer immunogenicity
Online Access:http://link.springer.com/article/10.1186/s13058-018-1054-3

Internet

http://link.springer.com/article/10.1186/s13058-018-1054-3

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