LRRC4 Suppresses E-Cadherin-Dependent Collective Cell Invasion and Metastasis in Epithelial Ovarian Cancer

LRRC4 Suppresses E-Cadherin-Dependent Collective Cell Invasion and Metastasis in Epithelial Ovarian Cancer

Epithelial ovarian cancer (EOC) is the most malignant gynecological carcinoma and is of a high incidence of death due to detection at late stages when metastasis already occurs. However, the mechanism underlying metastasis of EOC remains unclear. Analysis of the open database and experiments with im...

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Bibliographic Details
Main Authors: Chunhua Zhao, Xiaoling She, Yan Zhang, Changhong Liu, Peiyao Li, Shuai Chen, Buqing Sai, Yunchao Li, Jianbo Feng, Jia Liu, Yingnan Sun, Songshu Xiao, Liping Li, Minghua Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
collective invasion and metastasis
epithelial ovarian cancer
LRRC4
PIK3R1
E-cadherin
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00144/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00144/full

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