High dose sertraline monotherapy fails to protect rhesus macaques from lethal challenge with Ebola virus Makona

Abstract The recent epidemic of Ebola virus disease in West Africa resulted in an unprecedented number of cases and deaths. Due to the scope of the outbreak combined with the lack of available approved treatment options, there was strong motivation to investigate any potential drug which had existin...

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Bibliographic Details
Main Authors: Anna N. Honko, Joshua C. Johnson, Jonathan S. Marchand, Louis Huzella, Ricky D. Adams, Nicholas Oberlander, Lisa M. Torzewski, Richard S. Bennett, Lisa E. Hensley, Peter B. Jahrling, Gene G. Olinger
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06179-y