Sex-Specific Cannabidiol- and Iloperidone-Induced Neuronal Activity Changes in an In Vitro MAM Model System of Schizophrenia

Sex-Specific Cannabidiol- and Iloperidone-Induced Neuronal Activity Changes in an In Vitro MAM Model System of Schizophrenia

Cortical circuit dysfunction is thought to be an underlying mechanism of schizophrenia (SZ) pathophysiology with normalization of aberrant circuit activity proposed as a biomarker for antipsychotic efficacy. Cannabidiol (CBD) shows potential as an adjunctive antipsychotic therapy; however, potential...

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Bibliographic Details
Main Authors: Rachel-Karson Thériault, Myles St-Denis, Tristen Hewitt, Jibran Y. Khokhar, Jasmin Lalonde, Melissa L. Perreault
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
schizophrenia
cannabidiol
iloperidone
haloperidol
electrophysiology
primary cortical neurons
Online Access:https://www.mdpi.com/1422-0067/22/11/5511

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https://www.mdpi.com/1422-0067/22/11/5511

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