Association of serum high-mobility group box protein 1 level with outcomes of acute exacerbation of idiopathic pulmonary fibrosis and fibrosing nonspecific interstitial pneumonia.

High-mobility group box 1 (HMGB1) protein is important in acute lung injury. However, the role of HMGB-1 in acute exacerbation of fibrosing interstitial pneumonia (AE-FIP) has not been adequately studied.We prospectively measured serum HMGB1 level from disease onset to day 7 in 36 patients with AE-F...

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Bibliographic Details
Main Authors: Hiroshige Shimizu, Susumu Sakamoto, Takuma Isshiki, Kenta Furuya, Atsuko Kurosaki, Sakae Homma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5967827?pdf=render