Modular self-assembly of gamma-modified peptide nucleic acids in organic solvent mixtures

Nucleic acid-based materials are usually only compatible with aqueous solutions. Here, the authors show a structural nucleic acid nanotechnology using gamma-modified peptide nucleic acids that enables formation of solvent-compatible, self-assembling nanostructures defined by Watson-Crick base pairin...

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Bibliographic Details
Main Authors: Sriram Kumar, Alexander Pearse, Ying Liu, Rebecca E. Taylor
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16759-8