Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore

Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore

Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have been developed in pediatric or adult non-critically ill patients, resp...

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Bibliographic Details
Main Authors: Cornelia Knaak, Peter Nyvlt, Friederike S. Schuster, Claudia Spies, Patrick Heeren, Thomas Schenk, Felix Balzer, Paul La Rosée, Gritta Janka, Frank M. Brunkhorst, Didier Keh, Gunnar Lachmann
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Critical Care
Subjects:
Hemophagocytic lymphohistiocytosis (HLH)
Macrophage activation syndrome (MAS)
Hemophagocytic syndrome (HPS)
Intensive care unit (ICU)
HLH-2004 criteria
HScore
Online Access:http://link.springer.com/article/10.1186/s13054-020-02941-3

Internet

http://link.springer.com/article/10.1186/s13054-020-02941-3

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