Mitochondrial associated ubiquitin fold modifier-1 mediated protein conjugation in Leishmania donovani.

In this report, we demonstrate the existence of the ubiquitin fold modifier-1 (Ufm1) and its conjugation pathway in trypanosomatid parasite Leishmania donovani. LdUfm1 is activated by E1-like enzyme LdUba5. LdUfc1 (E2) specifically interacted with LdUfm1 and LdUba5 to conjugate LdUfm1 to proteinaceo...

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Bibliographic Details
Main Authors: Sreenivas Gannavaram, Paresh Sharma, Robert C Duncan, Poonam Salotra, Hira L Nakhasi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3021533?pdf=render