Investigation of FOXP3 genetic variations at positions -2383 C/T and IVS9+459 T/C in southern Iranian patients with lung carcinoma

Investigation of FOXP3 genetic variations at positions -2383 C/T and IVS9+459 T/C in southern Iranian patients with lung carcinoma

Objective(s): FOXP3 gene is an X-linked gene that encodes FOXP3 protein, an essential transcription factor in CD4+CD25+FOXP3+ regulatory T (Treg) cells.  We aimed, in the present study, to investigate the association of two FOXP3 polymorphisms, -2383 C/T (rs3761549) and IVS9+459 T/C (rs2280883), wit...

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Bibliographic Details
Main Authors: Maryam Fazelzadeh Haghighi, Mohammad Ali Ghayumi, Farzane Behzadnia, Nasrollah Erfani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
FOXP3 gene
Gene polymorphism
Lung cancer
PCR-RFLP
Online Access:http://ijbms.mums.ac.ir/pdf_4408_c2c27df49b39fa904154a578f62dfecb.html

Internet

http://ijbms.mums.ac.ir/pdf_4408_c2c27df49b39fa904154a578f62dfecb.html

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