The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

Abstract Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes encode a protein family (SPANX-A, -B, -C and -D), whose expression is limited to the testis and spermatozoa in normal tissues and various tumour cells. SPANX-A/D proteins have been detected in metastatic melan...

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Main Authors: Itziar Urizar-Arenaza, Aitor Benedicto, Arantza Perez-Valle, Nerea Osinalde, Vyacheslav Akimov, Iraia Muñoa-Hoyos, Jose Antonio Rodriguez, Aintzane Asumendi, Maria Dolores Boyano, Blagoy Blagoev, Irina Kratchmarova, Nerea Subiran
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83169-1

Internet

https://doi.org/10.1038/s41598-021-83169-1

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