High methylation of lysine acetyltransferase 6B is associated with the Cobb angle in patients with congenital scoliosis

High methylation of lysine acetyltransferase 6B is associated with the Cobb angle in patients with congenital scoliosis

Abstract Background The etiology of congenital scoliosis (CS) is complex and uncertain. Abnormal DNA methylation affects the growth and development of spinal development. In this study, we investigated the role of DNA methylation in CS. Methods The target region DNA methylation level in the peripher...

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Bibliographic Details
Main Authors: Yuantao Wu, Hongqi Zhang, Mingxing Tang, Chaofeng Guo, Ang Deng, Jiong Li, Yunjia Wang, Lige Xiao, Guanteng Yang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Translational Medicine
Subjects:
Congenital scoliosis
Epigenetic
DNA methylation
Lysine acetyltransferase 6B
RUNX2
Online Access:http://link.springer.com/article/10.1186/s12967-020-02367-z

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http://link.springer.com/article/10.1186/s12967-020-02367-z

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