Prognostic Relevance of Promoter Hypermethylation of Multiple Genes in Breast Cancer Patients

Background: Methylation-mediated suppression of detoxification, DNA repair and tumor suppressor genes has been implicated in cancer development. This study was designed to investigate the impact of concurrent methylation of multiple genes in breast tumors on disease prognosis.

Bibliographic Details
Main Authors: Gayatri Sharma, Sameer Mirza, Yi-Hsin Yang, Rajinder Parshad, Priya Hazrah, Siddartha Datta Gupta, Ranju Ralhan
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0507