Expression patterns of bovine CD1 in vivo and assessment of the specificities of the anti-bovine CD1 antibodies.

Research addressing the in vivo effects of T cell activation by lipids, glycolipids, and lipopeptides is hampered by the absence of a suitable animal model. Mice and rats do not express CD1a, CD1b, and CD1c molecules that present pathogen-derived lipid antigens in humans. In cattle, two CD1A and thr...

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Bibliographic Details
Main Authors: Thi Kim Anh Nguyen, Peter Reinink, Chema El Messlaki, Jin S Im, Altan Ercan, Steven A Porcelli, Ildiko Van Rhijn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376853?pdf=render