Host responses to sepsis vary in different low-lethality murine models.

Animal models for the study of sepsis are being increasingly scrutinized, despite their essential role for early translational research. In particular, recent studies have suggested that at the level of the leukocyte transcriptome, murine models of burns, trauma and endotoxemia markedly differ from...

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Bibliographic Details
Main Authors: Lori F Gentile, Dina C Nacionales, M Cecilia Lopez, Erin Vanzant, Angela Cuenca, Benjamin E Szpila, Alex G Cuenca, Anna Joseph, Frederick A Moore, Christiaan Leeuwenburgh, Henry V Baker, Lyle L Moldawer, Philip A Efron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4006924?pdf=render