Participation of NADPH Oxidase-Related Reactive Oxygen Species in Leptin-Promoted Pulmonary Inflammation: Regulation of cPLA2α and COX-2 Expression
Obesity is a worldwide epidemic problem and correlates to varieties of acute or chronic lung diseases such as acute respiratory distress syndrome, chronic obstructive pulmonary disease, and pulmonary fibrosis. An increase of leptin, a kind of adipokine, in lean mice plasma has been found to impair i...
Main Authors: | Pei-Sung Hsu, Chia-Mo Lin, Jia-Feng Chang, Chi-Sheng Wu, Kee-Chin Sia, I-Ta Lee, Kuo-Yang Huang, Wei-Ning Lin |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/20/5/1078 |
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