Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

Abstract Background Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoite-derived 18S rRNA persists in peripheral blood. If present in blood...

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Bibliographic Details
Main Authors: Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman, Robert A. Seder
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Subjects:
18S rRNA
SSU
Small subunit rRNA
Plasmodium
Molecular diagnostic
Online Access:http://link.springer.com/article/10.1186/s12936-018-2422-2

Internet

http://link.springer.com/article/10.1186/s12936-018-2422-2

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