Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis

Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis

Tuberculosis (TB) continues to be the leading cause of deaths due to its persistent drug resistance and the consequent ineffectiveness of anti-TB treatment. Recent years witnessed huge amount of sequencing data, revealing mutations responsible for drug resistance. However, the lack of an up-to-date...

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Bibliographic Details
Main Authors: Pooja Singh, Salma Jamal, Faraz Ahmed, Najumu Saqib, Seema Mehra, Waseem Ali, Deodutta Roy, Nasreen Z. Ehtesham, Seyed E. Hasnain
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Tuberculosis
Genome sequencing
MDR
MycoTRAP-DB
Secondary mutations
SNPs
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702100146X

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http://www.sciencedirect.com/science/article/pii/S200103702100146X

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