Vascular Mimicry: A Novel Neovascularization Mechanism Driving Anti-Angiogenic Therapy (AAT) Resistance in Glioblastoma

Glioblastoma (GBM) is a hypervascular neoplasia of the central nervous system with an extremely high rate of mortality. Owing to its hypervascularity, anti-angiogenic therapies (AAT) have been used as an adjuvant to the traditional surgical resection, chemotherapy, and radiation. The benefits of AAT...

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Bibliographic Details
Main Authors: Kartik Angara, Thaiz F. Borin, Ali S. Arbab
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331730133X