Ethical considerations in conducting surgical research in severe complicated intra-abdominal sepsis

Ethical considerations in conducting surgical research in severe complicated intra-abdominal sepsis

Abstract Background Severe complicated intra-abdominal sepsis (SCIAS) has high mortality, thought due in part to progressive bio-mediator generation, systemic inflammation, and multiple organ failure. Treatment includes early antibiotics and operative source control. At surgery, open abdomen managem...

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Bibliographic Details
Main Authors: Christopher J. Doig, Stacey A Page, Jessica L. McKee, Ernest E. Moore, Fikri M. Abu-Zidan, Rosemary Carroll, John C. Marshall, Peter D Faris, Matti Tolonen, Fausto Catena, Federico Coccolini, Massimo Sartelli, Luca Ansaloni, Sam F. Minor, Bruno M. Peirera, Jose J Diaz, Andrew W. Kirkpatrick, the Closed Or Open after Laparotomy (COOL) after Source Control for Severe Complicated Intra-Abdominal Sepsis Investigators
Format: Article
Language:English
Published: BMC 2019-08-01
Series:World Journal of Emergency Surgery
Subjects:
Intra-peritoneal sepsis
Open-abdomen
Randomized controlled trial
Multiple organ dysfunction
Consent
Waiver
Online Access:http://link.springer.com/article/10.1186/s13017-019-0259-9

Internet

http://link.springer.com/article/10.1186/s13017-019-0259-9

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