RIPK3-Dependent Necroptosis Limits PRV Replication in PK-15 Cells

RIPK3-Dependent Necroptosis Limits PRV Replication in PK-15 Cells

Pigs infected by pseudorabies virus (PRV) display necrotic pathology in multiple organs. The mechanism by which PRV induces cell death is still unclear. Recently, necroptosis was identified as a programmed process dependent on the receptor interacting protein kinase 3 (RIPK3) and mixed lineage kinas...

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Bibliographic Details
Main Authors: Hongchao Gou, Zhibiao Bian, Rujian Cai, Pinpin Chu, Shuai Song, Yan Li, Zhiyong Jiang, Kunli Zhang, Dongxia Yang, Chunling Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
pseudorabies virus (PRV)
necroptosis
receptor interacting protein kinase 3 (RIPK3)
mixed lineage kinase-like protein (MLKL)
PK-15 cell
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.664353/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.664353/full

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