In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19 [version 1; peer review: 2 approved]

Background: Human coronavirus (SARS-CoV-2) is causing a pandemic with significant morbidity and mortality. As no effective novel drugs are available currently, drug repurposing is an alternative intervention strategy. Here we present an in silico drug repurposing study that implements successful con...

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Bibliographic Details
Main Authors: Bharath BR, Hrishikesh Damle, Shiban Ganju, Latha Damle
Format: Article
Language:English
Published: F1000 Research Ltd 2020-07-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-663/v1