Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota

Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota

Abstract Background and Aims To explore the inhibition mechanism of Saccharomyces boulardii (S. boulardii) on ulcerative colitis (UC) carcinogenesis. Methods C57BL/6 mice were treated with azoxymethane and dextran sulfate sodium (AOM/DSS) to develop a UC carcinogenesis model. The treatment group was...

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Bibliographic Details
Main Authors: Chunsaier Wang, Wenbin Li, Hongying Wang, Yiming Ma, Xinhua Zhao, Xudong Zhang, Hong Yang, Jiaming Qian, Jingnan Li
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Microbiology
Subjects:
Ulcerative colitis carcinogenesis
TNF-α
IL-6
Saccharomyces boulardii
Intestinal microbiota
Online Access:http://link.springer.com/article/10.1186/s12866-019-1610-8

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http://link.springer.com/article/10.1186/s12866-019-1610-8

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