Human papillomavirus 16 non-European variants are preferentially associated with high-grade cervical lesions.

HPV16 accounts for 50-70% of cervical cancer cases worldwide. Characterization of HPV16 variants previously indicated that they differ in risks for viral persistence, progression to cervical precancer and malignant cancer. The aim of this study was to examine the association of severity of disease w...

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Bibliographic Details
Main Authors: Luciana Bueno Freitas, Zigui Chen, Elaine Freire Muqui, Neide Aparecida Tosato Boldrini, Angélica Espinosa Miranda, Liliana Cruz Spano, Robert D Burk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077691?pdf=render