Salbutamol Worsens the Autonomic Nervous System Dysfunction of Children With Sickle Cell Disease

Salbutamol Worsens the Autonomic Nervous System Dysfunction of Children With Sickle Cell Disease

BackgroundSickle cell disease (SCD) patients with asthma have an increased rate of vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) episodes when compared to those without asthma. We hypothesized that either asthma diagnosis or bronchodilator treatment might aggravate SCD via their modulat...

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Bibliographic Details
Main Authors: Plamen Bokov, Houmam El Jurdi, Isabelle Denjoy, Claudine Peiffer, Noria Medjahdi, Laurent Holvoet, Malika Benkerrou, Christophe Delclaux
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
sickle cell disease
asthma
salbutamol
heart rate variability
sympathetic activity
vagal activity
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00031/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00031/full

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