Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension

Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH), characterized by localized increased arterial blood pressure in the lungs, is a slow developing long-term disease that can be fatal. PAH is characterized by inflammation, vascular tone imbalance, pathological pulmonary vascular remodeling, and right-sided heart...

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Bibliographic Details
Main Authors: R.C.P. Luna, Y. de Oliveira, J.V.C. Lisboa, T.R. Chaves, T.A.M. de Araújo, E.E. de Sousa, M. Miranda Neto, L. Pirola, V.A. Braga, J.L. de Brito Alves
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Epigenetic
Pulmonary arterial hypertension
DNA Methylation
Histone acetylation
miRNAs
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200301&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200301&lng=en&tlng=en

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