Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets

Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets

Background: Synovial inflammation is associated with pain severity in patients with knee osteoarthritis (OA). The aim here was to determine in a population with knee OA, whether synovial tissue from areas associated with pain exhibited different synovial fibroblast subsets, compared to synovial tiss...

Full description

Bibliographic Details
Main Authors: Dominika E Nanus, Amel Badoume, Susanne N Wijesinghe, Andrea M Halsey, Patrick Hurley, Zubair Ahmed, Rajesh Botchu, Edward T Davis, Mark A Lindsay, Simon W Jones
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:EBioMedicine
Subjects:
scRNAseq
Osteoarthritis
Synovial fibroblasts
Obesity
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421004114

Internet

http://www.sciencedirect.com/science/article/pii/S2352396421004114

Similar Items