Circular Trajectory Reconstruction Uncovers Cell‐Cycle Progression and Regulatory Dynamics from Single‐Cell Hi‐C Maps

Abstract Single‐cell Hi‐C technology is emerging and will provide unprecedented opportunities to elucidate chromosomal dynamics with high resolution. How to characterize pseudo time‐series of single cells using single‐cell Hi‐C maps is an essential and challenging topic. To this end, a powerful circ...

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Bibliographic Details
Main Authors: Yusen Ye, Lin Gao, Shihua Zhang
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201900986