A role for the canonical nuclear factor-κB pathway in coupling neurotrophin-induced differential survival of developing spiral ganglion neurons

A role for the canonical nuclear factor-κB pathway in coupling neurotrophin-induced differential survival of developing spiral ganglion neurons

Neurotrophins are key players of neural development by controlling cell death programs. However, the signaling pathways that mediate their selective responses in different populations of neurons remain unclear. In the mammalian cochlea, sensory neurons differentiate perinatally into type I and type...

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Bibliographic Details
Main Authors: Renaud eVandenbosch, Eva eChocholova, Pierre eRobe, Yiqiao eWang, Cecile eLambert, Gustave eMoonen, Francois eLallemend, Brigitte eMalgrange, Saida eHadjab
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cochlea
development
NF-κB
neurotrophins
spiral ganglion neurons
neuronal survival
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00242/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00242/full

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