Immune response and protective effect against chronic Toxoplasma gondii infection induced by vaccination with a DNA vaccine encoding profilin

Immune response and protective effect against chronic Toxoplasma gondii infection induced by vaccination with a DNA vaccine encoding profilin

Abstract Background Toxoplasma gondii is an obligate intracellular parasite that can infect almost all warm-blooded animals. T. gondii profilin (TgPF) plays a crucial role in parasite motility and host cell invasion, and has shown promise against toxoplasmosis. DNA vaccine was considered to elicit e...

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Bibliographic Details
Main Authors: Qi Gao, Nian-Zhang Zhang, Fu-Kai Zhang, Meng Wang, Ling-Ying Hu, Xing-Quan Zhu
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Infectious Diseases
Subjects:
Toxoplasma gondii
Profilin
Immunogenicity
DNA vaccine
Chronic toxoplasmosis
Online Access:http://link.springer.com/article/10.1186/s12879-018-3022-z

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http://link.springer.com/article/10.1186/s12879-018-3022-z

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