Targeting chemokines for acute lymphoblastic leukemia therapy

Targeting chemokines for acute lymphoblastic leukemia therapy

Abstract Acute lymphoblastic leukemia (ALL) is a hematological malignancy characterized by the malignant clonal expansion of lymphoid hematopoietic precursors. It is regulated by various signaling molecules such as cytokines and adhesion molecules in its microenvironment. Chemokines are chemotactic...

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Bibliographic Details
Main Authors: Zixi Hong, Zimeng Wei, Tian Xie, Lin Fu, Jiaxing Sun, Fuling Zhou, Muhammad Jamal, Qiuping Zhang, Liang Shao
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Hematology & Oncology
Subjects:
Acute lymphoblastic leukemia
Chemokine
Microenvironment
Therapeutic targets
Online Access:https://doi.org/10.1186/s13045-021-01060-y

Internet

https://doi.org/10.1186/s13045-021-01060-y

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