Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination

Summary: Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3′ end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the underlying termination mechanism is not yet understood. Here, we demonstrate that the conserved and essential ter...

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Bibliographic Details
Main Authors: Tea Kecman, Krzysztof Kuś, Dong-Hyuk Heo, Katie Duckett, Adrien Birot, Sabrina Liberatori, Shabaz Mohammed, Lucia Geis-Asteggiante, Carol V. Robinson, Lidia Vasiljeva
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314220