Linking yeast Gcn5p catalytic function and gene regulation using a quantitative, graded dominant mutant approach.

Linking yeast Gcn5p catalytic function and gene regulation using a quantitative, graded dominant mutant approach.

Establishing causative links between protein functional domains and global gene regulation is critical for advancements in genetics, biotechnology, disease treatment, and systems biology. This task is challenging for multifunctional proteins when relying on traditional approaches such as gene deleti...

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Bibliographic Details
Main Authors: Amanda M Lanza, John J Blazeck, Nathan C Crook, Hal S Alper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338614?pdf=render

Internet

http://europepmc.org/articles/PMC3338614?pdf=render

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