Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine

The meso-cortico-limbic system, via dopamine release, encodes the rewarding and reinforcing properties of natural rewards. It is also activated in response to abused substances and is believed to support drug-related behaviors. Dysfunctions of this system lead to several psychiatric conditions inclu...

Full description

Bibliographic Details
Main Authors: Sebastien eParnaudeau, Marie-Louise eDongelmans, Marc eTuriault, Frederic eAmbroggi, Anne-Sophie eDelbes, Celine eCansell, Serge H Luquet, Pier Vincenzo Piazza, Francois eTronche, Jacques eBARIK
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00035/full