Recipients with In Utero Induction of Tolerance Upregulated MHC Class I in the Engrafted Donor Skin
The alterations in MHC class I expression play a crucial step in immune evasion of cancer or virus-infected cells. This study aimed to examine whether tolerized grafts modified MHC class I expression. FVB/N mice were rendered tolerant of C57BL/6 alloantigens by in utero transplantation of C57BL/6 ma...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2014-01-01
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| Series: | Disease Markers |
| Online Access: | http://dx.doi.org/10.1155/2014/531092 |