Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivorsResearch in context

Background: Reduced activity of proprotein convertase subtilisin/kexin type 9 (PCSK9) has been associated with decreased short-term death in patients with septic shock. Whether PCSK9 genotype influences long-term outcomes in sepsis survivors is unknown. Methods: We evaluated the impact of PCSK9 loss...

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Bibliographic Details
Main Authors: Kelly Roveran Genga, Cody Lo, Mihai S. Cirstea, Fernando Sergio Leitao Filho, Keith R. Walley, James A. Russell, Adam Linder, Gordon A. Francis, John H. Boyd
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830536X