Metabolic Products of Linalool and Modulation of GABAA Receptors

Terpenoids are major subcomponents in aroma substances which harbor sedative physiological potential. We have demonstrated that various monoterpenoids such as the acyclic linalool enhance GABAergic currents in an allosteric manner in vitro upon overexpression of inhibitory α1β2 GABAA receptors in va...

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Bibliographic Details
Main Authors: Sinem Milanos, Shaimaa A. Elsharif, Dieter Janzen, Andrea Buettner, Carmen Villmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2017.00046/full