Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.

Standard treatment for osteosarcoma patients consists of a combination of cisplatin, adriamycin, and methotrexate before surgical resection of the primary tumour, followed by postoperative chemotherapy including vincristine and cyclophosphamide. Unfortunately, many patients still relapse or suffer a...

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Main Authors: Daniela Caronia, Ana Patiño-Garcia, Antonio Peréz-Martínez, Guillermo Pita, Leticia Tais Moreno, Marta Zalacain-Díez, Blanca Molina, Isabel Colmenero, Luis Sierrasesúmaga, Javier Benítez, Anna Gonzalez-Neira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3189235?pdf=render