Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform

The KRAS oncogene is involved in the pathogenesis of several types of cancer, particularly colorectal cancer (CRC). The most frequent mutations in this gene are associated with poor survival, increased tumor aggressiveness and resistance to therapy with anti-epidermal growth factor receptor (EGFR) a...

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Bibliographic Details
Main Authors: Maria Guarnaccia, Rosario Iemmolo, Floriana San Biagio, Enrico Alessi, Sebastiano Cavallaro
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Sensors
Subjects:
PCR
Online Access:http://www.mdpi.com/1424-8220/18/1/131