Genetic structures of copy number variants revealed by genotyping single sperm.

Genetic structures of copy number variants revealed by genotyping single sperm.

Copy number variants (CNVs) occupy a significant portion of the human genome and may have important roles in meiotic recombination, human genome evolution and gene expression. Many genetic diseases may be underlain by CNVs. However, because of the presence of their multiple copies, variability in co...

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Bibliographic Details
Main Authors: Minjie Luo, Xiangfeng Cui, David Fredman, Anthony J Brookes, Marco A Azaro, Danielle M Greenawalt, Guohong Hu, Hui-Yun Wang, Irina V Tereshchenko, Yong Lin, Yue Shentu, Richeng Gao, Li Shen, Honghua Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2668179?pdf=render

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http://europepmc.org/articles/PMC2668179?pdf=render

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