Plk4-dependent phosphorylation of STIL is required for centriole duplication

Plk4-dependent phosphorylation of STIL is required for centriole duplication

Duplication of centrioles, namely the formation of a procentriole next to the parental centriole, is regulated by the polo-like kinase Plk4. Only a few other proteins, including STIL (SCL/TAL1 interrupting locus, SIL) and Sas-6, are required for the early step of centriole biogenesis. Following Plk4...

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Bibliographic Details
Main Authors: Anne-Sophie Kratz, Felix Bärenz, Kai T. Richter, Ingrid Hoffmann
Format: Article
Language:English
Published: The Company of Biologists 2015-02-01
Series:Biology Open
Subjects:
Plk4
STIL
Centriole duplication
Phosphorylation
Centrosome
Online Access:http://bio.biologists.org/content/4/3/370

Internet

http://bio.biologists.org/content/4/3/370

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