The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis

Abstract Monocytes/macrophages have been found to be an important component of colitis. However, the key chemokine that initiates the CCR2+ monocytes migration from circulation to colitis tissue remains to be undiscovered. PC3-secreted microprotein (PSMP) is a novel chemokine whose receptor is CCR2....

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Bibliographic Details
Main Authors: Xiaolei Pei, Danfeng Zheng, Shaoping She, Jing Ma, Changyuan Guo, Xiaoning Mo, Yingmei Zhang, Quansheng Song, Yu Zhang, Dalong Ma, Ying Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05255-7