miR-124-3p Inhibits Microglial Secondary Inflammation After Basal Ganglia Hemorrhage by Targeting TRAF6 and Repressing the Activation of NLRP3 Inflammasome

miR-124-3p Inhibits Microglial Secondary Inflammation After Basal Ganglia Hemorrhage by Targeting TRAF6 and Repressing the Activation of NLRP3 Inflammasome

Objectives: Intracerebral hemorrhage (ICH) represents a serious central nervous system emergency with high morbidity and mortality, and the basal ganglia is the most commonly affected brain region. Differentially expressed microRNAs (miRs) have recently been highlighted to serve as potential diagnos...

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Bibliographic Details
Main Authors: Yudan Fang, Xiaoqin Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neurology
Subjects:
microglia secondary inflammation
intracerebral hemorrhage in basal ganglia
miR-124-3p
TRAF6
NLRP3 inflammasome
inflammatory factors
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.653321/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.653321/full

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