A Novel Chemically Modified Curcumin Reduces Severity of Experimental Periodontal Disease in Rats: Initial Observations

Tetracycline-based matrix metalloproteinase- (MMP-) inhibitors are currently approved for two inflammatory diseases, periodontitis and rosacea. The current study addresses the therapeutic potential of a novel pleiotropic MMP-inhibitor not based on an antibiotic. To induce experimental periodontitis,...

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Bibliographic Details
Main Authors: Muna S. Elburki, Carlos Rossa, Morgana R. Guimaraes, Mark Goodenough, Hsi-Ming Lee, Fabiana A. Curylofo, Yu Zhang, Francis Johnson, Lorne M. Golub
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/959471