Newly identified aspects of tumor suppression by RB

The retinoblastoma (RB) tumor suppressor belongs to a cellular pathway that plays a crucial role in restricting the G1-S transition of the cell cycle in response to a large number of extracellular and intracellular cues. Research in the last decade has highlighted the complexity of regulatory networ...

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Bibliographic Details
Main Authors: Patrick Viatour, Julien Sage
Format: Article
Language:English
Published: The Company of Biologists 2011-09-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/5/581